Pore-blockade Times for Field-Driven Polymer Translocation

نویسندگان

  • Henk Vocks
  • Debabrata Panja
  • Gerard T. Barkema
  • Robin C. Ball
چکیده

We study pore blockade times for a translocating polymer of length N , driven by a field E across the pore in three dimensions. The polymer performs Rouse dynamics, i.e., we consider polymer dynamics in the absence of hydrodynamical interactions. We find that the typical time the pore remains blocked during a translocation event scales as∼ N /E, where ν ≃ 0.588 is the Flory exponent for the polymer. In line with our previous work, we show that this scaling behavior stems from the polymer dynamics at the immediate vicinity of the pore — in particular, the memory effects in the polymer chain tension imbalance across the pore. This result, along with the numerical results by several other groups, violates the lower bound ∼ N/E suggested earlier in the literature. We discuss why this lower bound is incorrect and show, based on conservation of energy, that the correct lower bound for the pore-blockade time for field-driven translocation is given by ηN/E, where η is the viscosity of the medium surrounding the polymer. PACS numbers: 36.20.-r, 82.35.Lr, 87.15.Aa Field-driven Polymer Translocation 2

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تاریخ انتشار 2007